Pressure-Volume Analysis

Hemodynamics acquired by high fidelity pressure-volume admittance catheters offer beat-to-beat analysis of complete cardiac function. The UAPC utilizes Transonic Scisence Pressure Volume Catheters for terminal hemodynamic studies.  Left ventricle catheterization with pressure-volume transducers is commonly utilized to assess basal left ventricle functions such as ionotropy and lusitropy. The generation of pressure-volume loops offers the unique advantage of enabling a more specific measure of cardiac performance independent of loading conditions and heart rate, which is not possible with other approaches such as echocardiography. Pressure-volume analysis allows for calculation of indices of systolic and diastolic function such as:

  • cardiac output
  • work
  • power
  • end systolic pressure-volume relationship (ESPVR)
  • end diastolic pressure-volume relationship (EDPVR)
  • end systolic elastance (Ees)
  • arterial elastance (Ea)
  • max and min dP/dt
  • preload-recruitable stroke work (PRSW)
  • tau


Tail Cuff
Tail-cuff Blood Pressure System (available soon)

The tail-cuff blood pressure system offers an accurate and non-invasive measurement of systolic, diastolic, mean arterial pressures, and pulse rate in conscious mice. Up to 4 mice can be monitored simultaneously.

For a complete list of hemodynamic services offered, Contact Us or see our Hemodynamic Request Form.